DOI: http://dx.doi.org/10.1016/j.maturitas.2017.02.011

Angelo Cagnacci^, ,  Federica Palma,  Antonella Napolitano,  Anjeza Xholli

Objective

To evaluate whether climacteric symptoms are related to pelvic organ prolapse (POP) in postmenopausal women.

Study Design

A cross-sectional investigation was performed of 1382 postmenopausal women attending an outpatient service for menopause at a university hospital.

Main Outcome Measures

Data regarding climacteric symptoms, as captured by the Greene Climacteric Scale, and objective POP were retrieved from an electronic database. Additional data retrieved were age, anthropometric measures, personal and reproductive history, use of medication or drugs, coffee, smoking, state of anxiety (STAI scale score) and depression (Zung scale score).

Results

The score on Greene Climacteric Scale was higher (p = 0.02) in women with (n = 538) than in those without (n = 844) POP (29.6 ± 13.6 vs. 27.8 ± 13.; p = 0.02). In multiple logistic regression models, the score was independently related to POP as a whole (OR 1.012; 95%CI 1.003,1.022; p = 0.009), and to bladder prolapse (OR 1.011; 95%CI 1.007,1.07; p = 0.02) but not to uterus prolapse (OR 1.003; 95%CI 0.99,1.016; p = 0.63) or rectum prolapse (rectocele) (OR 1.004; 95%CI 0.988,1.02; p = 0.62).

Conclusions

In postmenopausal women, a higher burden of climacteric symptoms, is associated with POP. Underlying mechanisms were not assessed and deserve further investigation.

資料來源：Maturitas