Maturitas. 2016 Dec;94:137-142. doi: 10.1016/j.maturitas.2016.10.004. Epub 2016 Oct 5.
 

Lampio L¹, Saaresranta T², Engblom J³, Polo O⁴, Polo-Kantola P⁵.

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Abstract

OBJECTIVE:

This follow-up study aimed to evaluate risk factors for menopausal sleep disturbances already identifiable before menopause.

METHODS:

At baseline, all 81 women were premenopausal. At year-five follow-up, 27 of the women were premenopausal, 40 postmenopausal, and 14 postmenopausal and using hormone therapy. We used the Basic Nordic Sleep Questionnaire to study sleep; additional questionnaires evaluated risk factors for sleep impairment.

RESULTS:

Sleep quality differed only marginally between the groups. The following baseline variables were associated with impaired sleep quality at follow-up: depressive symptoms increased the risk of nocturnal awakenings (OR 1.16 (95%CI 1.02-1.32), p=0.025), morning tiredness (OR 1.22 (95%CI 1.06-1.40), p=0.007), daytime tiredness (OR 1.24 (95%CI 1.06-1.44), p=0.007) and propensity to fall asleep during work or leisure time (OR 1.18 (95%CI 1.01-1.37), p=0.036). Personal crises increased the risk of longer sleep latency (OR 5.46 (95%CI 1.13-26.32), p=0.035) and of propensity to fall asleep when not active (OR 5.41 (95%CI 1.42-20.83), p=0.014). Use of medications affecting the CNS increased the risk of worse general sleep quality (OR 11.44 (95% CI 1.07-121.79), p=0.044). Perceived impaired general health (OR 2.87 (95%CI 1.04-7.94), p=0.043) and frequent night sweats (OR 10.50 (95%CI 2.25-49.01), p=0.003) increased the risk of difficulty falling asleep.

CONCLUSIONS:

Various premenopausal health-related factors seem to predict poor sleep in menopausal transition. Menopause itself appears to have only minor effects. Thus, it is essential to identify high-risk women to allow timely interventions that may prevent the development of sleep disturbances at menopause.

Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

KEYWORDS:

CNS medication; Depressive symptoms; Menopause; Night sweats; Perceived impaired health; Personal crises; Sleep disturbances

PMID: 27823734 DOI: 10.1016/j.maturitas.2016.10.004
資料來源：PubMed